"Isabella", the gorilla referred to as "she" throughout the film, has no breasts, and has a head crest and "silverback" grey hair, all exclusively male characteristics. She's a he.
It could have been a male gorilla, but they only named it Isabella for another purpose. Isabella might be an egg. Isabella might be the name of the first character to go invisible in a novel or something. You never know, Isabella might be a girls name to one of Steven Kings characters that went invisible, 'cos I think thats where it sounds familiar to, I may be wrong though. Still, I know, stupid name for an animal of the opposite sex.
Anonymous is right. The gorilla is referred to as a female throughout - "She is out again ... " "Her blood pressure ... " and so on. Also, when Caine is (briefly) reconstituted the special effects people were careful to give him a p*nis, forming layer by layer. Isabella doesn't have one. "He" should have, or "she" should lack the overt male characteristics mentioned above.
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